People


Yves Le Guennec

Institution System X
GroupFormer members of the LINCS

Books And Theses

Transient dynamics of beam trusses under impulse loads Dynamique transitoire des treillis de poutres soumis à des chargements impulsionnels,
Yves Le Guennec,
2013

Articles

Design of a commercial aircraft environment control system using Bayesian optimization techniques,
Paul Feliot, Yves Le Guennec, Julien Bect, Emmanuel Vazquez,
EngOpt 2016, 5th International Conference on Engineering Optimization 2016, Iguassu Falls, Brazil
A time-reversal process for beam trusses subjected to impulse loads,
Yves Le Guennec, Eric Savin, Didier Clouteau,
3rd International Workshop on New Computational Methods for Inverse Problems 2013, Paris, France
Transient dynamics of three-dimensional beam trusses under impulse loads,
Yves Le Guennec, Eric Savin, Didier Clouteau,
meeting acoustical society of america 2012, Hong-Kong, France
TRANSIENT DYNAMICS OF THREE-DIMENSIONAL BEAM TRUSSES USING HIGHER ORDER KINEMATICS,
Yves Le Guennec, Eric Savin,
Internoise 2012/ASME NCAD meeting 2012, NYC, United States
Dynamique transitoire de treillis de poutres tridimensionnels soumis à des chargements impulsionnels,
Yves Le Guennec, Eric Savin,
10e colloque national en calcul des structures 2011, Giens, France

Journal articles

Biological activities of non-enzymatic oxygenated metabolites of polyunsaturated fatty acids (NEO-PUFAs) derived from EPA and DHA: New anti-arrhythmic compounds?,
Marie Galano, Jérôme Roy, Thierry Durand, Jetty Chung-Yung Lee, Jean-Yves Le Guennec, Camille Oger, Marie Demion,
Molecular Aspects of Medicine 2018
High Frequency Autonomic Modulation: a new model for analysis of autonomic cardiac control,
Pascal Champeroux, Pierre Fesler, Sébastien Judé, Serge Richard, Jean-Yves Le Guennec, Jérôme Thireau,
British Journal of Pharmacology 2018
A parametric and non-intrusive reduced order model of car crash simulation,
Yves Le Guennec , Jean-Patrick Brunet, Fatima Zohra Daim, Ming Chau, Yves Tourbier,
Computer Methods in Applied Mechanics and Engineering 2018
Corrigendum: Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety?,
Jean-Yves Le Guennec, Jérôme Thireau, Aude Ouillé, Julien Roussel, Jérôme Roy, Serge Richard, Sylvain Richard, Eric Martel, Pascal Champeroux,
Scientific Reports 2017
Two sides of the same coin: NEO-PUFAs in Rett syndrome and post-infarction cardiac arrhythmias,
Marie Demion, Camille Oger, Claire Vigor, Jérôme Thireau, Jean-Yves Le Guennec, Thierry Durand, Jean-Marie Galano, Jetty Chung-Yung Lee,
European Journal of Lipid Science and Technology 2017
Cardioprotective effects of omega 3 fatty acids: origin of the variability,
Jean-Yves Le Guennec, Jérôme Roy,
Journal of Muscle Research and Cell Motility 2017
Non-enzymatic oxidized metabolite of DHA, 4( RS )-4-F 4t -neuroprostane protects the heart against reperfusion injury,
Jean-Yves Le Guennec, Jérôme Roy, Jérémy Fauconnier, Camille Oger, Charlotte Farah, Claire Angebault-Prouteau, Jérôme Thireau, Patrice Bideaux, Valérie Scheuermann, Valérie Bultel-Poncé, Marie Demion, Jean-Marie Galano, Thierry Durand, Jetty Chung-Yung Lee,
Free Radical Biology and Medicine 2017
Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide,
Jean-Yves Le Guennec, Renata Tupinambá Branquinho, Jérôme Roy, Charlotte Farah, Giani Martins Garcia, Franck Aimond, Dênia Antunes Saude-Guimarães, Andrea Grabe-Guimaraes, Vanessa Carla Furtado Mosqueira, Marta De Lana, Sylvain Richard,
Scientific Reports 2017
Physiological role of reactive oxygen species as promoters of natural defenses,
Jean-Yves Le Guennec, Jérôme Roy, Jean-Marie Galano, Thierry Durand, Jetty Chung-Yung Lee,
FASEB Journal 2017
Reply to the Editor—Carnitine and Ventricular Repolarization: A Complex Link? Reply to the Editor-Carnitine and Ventricular Repolarization: A Complex Link?,
Julien Roussel, Jérôme Thireau, Charlotte Farah, Jean Yves Le Guennec, Dominique Babuty,
Heart Rhythm 2016
The Complex QT/RR Relationship in Mice,
Julien Roussel, Pascal Champeroux, Jérôme Roy, Sylvain Richard, Jérémy Fauconnier, Jean-Yves Le Guennec, Jérôme Thireau,
Scientific Reports 2016
Carnitine deficiency induces a short QT syndrome,
Julien Roussel, François Labarthe, Jérôme Thireau, Fabio Ferro, Charlotte Farah, Jérôme Roy, Masahisa Horiuchi, Martine Tardieu, Bruno Lefort, Jean François Benoist, Alain Lacampagne, Sylvain Richard, Jérémy Fauconnier, Dominique Babuty, Jean Yves Le Guennec,
Heart Rhythm 2016
Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid: Bioactive drugs?,
Jérôme Roy, Jean-Yves Le Guennec, Marie Galano, Jérôme Thireau, Valérie Bultel-Poncé, Marie Demion, Camille Oger, Jetty Chung-Yung Lee, Thierry Durand,
Biochimie 2016
Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety?,
Jean-Yves Le Guennec, Jérôme Thireau, Aude Ouillé, Julien Roussel, Jérôme Roy, Serge Richard, Sylvain Richard, Eric Martel, Pascal Champeroux,
Scientific Reports 2016
Assessment of Isoprostanes in Human Plasma: Technical Considerations and the Use of Mass Spectrometry,
Yiu Yiu Lee, Jean-Marie Galano, Camille Oger, Claire Vigor, Reversat Guillaume, Jérôme Roy, Jean-Yves Le Guennec, Thierry Durand, Jetty Chung-Yung Lee,
Lipids 2016
The high frequency relationship: implications for torsadogenic hERG blockers,
P Champeroux, Jean-Yves Le Guennec, S Jude, C Laigot, A Maurin, M-L Sola, J-S Fowler, Sylvain Richard, J Thireau,
British Journal of Pharmacology 2016
Non-enzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid,
Jérôme Roy, Camille Oger, Jérôme Thireau, Julien Roussel, Olivia Mercier-Touzet, Delinger Faure, Edith Pinot, Charlotte Farah, Douglass Taber, Jean-Paul Cristol, Jetty C.Y. Lee, Alain Lacampagne, Jean-Marie Galano, Thierry Durand, Jean-Yves Le Guennec,
Free Radical Biology and Medicine 2015
Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and α-linolenic acids; bioactivities and potential use as biomarkers,
Jean-Marie Galano, Jetty Chung-Yung Lee, Cécile Gladine, Blandine Comte, Jean-Yves Le Guennec, Camille Oger, Thierry Durand,
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 2015
Voltage-gated sodium channels and cancer: is excitability their primary role?,
Sébastien Roger, Ludovic Gillet, Jean-Yves Le Guennec, Pierre Besson,
Frontiers in Pharmacology 2015
Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase,
Julien Roussel, Jérôme Thireau, Cyril Brenner, Nathalie Saint, Valérie Scheuermann, A. Lacampagne, Jean-Yves Le Guennec, Jérémy Fauconnier,
Biochimica et Biophysica Acta - Molecular Basis of Disease 2015
Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries,
Ludovit Paulis, Jeremy Fauconnier, Olivier Cazorla, Jérome Thireau, Raffaella Soleti, Bastien Vidal, Aude Ouillé, Marion Bartholomé, Patrice Bideaux, François Roubille, Jean-Yves Le Guennec, Ramaroson Andriantsitohaina, Maria Carmen Martinez, Alain Lacampagne,
Scientific Reports 2015
Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation,
Jérôme Roy, Liliam Teixeira Oliveira, Camille Oger, Jean-Marie Galano, Valerie Bultel-Poncé, Sylvain Richard, Andrea Grabe Guimaraes, José Mário Carneiro Vilela, Margareth Spangler Andrade, Thierry Durand, Pierre Besson, Vanessa Carla Furtado Mosqueira, Jean-Yves Le Guennec,
Journal of Experimental and Clinical Cancer Research 2015
β-Adrenergic blockade combined with subcutaneous B-type natriuretic peptide: a promising approach to reduce ventricular arrhythmia in heart failure?,
Jean-Yves Le Guennec, Jérôme Thireau, Sarah Karam, Stéphanie Roberge, Julien Roussel, Franck Aimond, Cécile Cassan, Arnaud Gac, Dominique Babuty, Alain Lacampagne, Jérémy Fauconnier, Sylvain Richard,
Heart 2014
TNF- -mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes,
Jean-Yves Le Guennec, S. Roberge, J. Roussel, D. Andersson, A. Meli, B. Vidal, F. Blandel, J. Lanner, A. Katz, H. Westerblad, A. Lacampagne, J. Fauconnier,
Cardiovascular Research 2014
Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization,
Jean-Yves Le Guennec, Virginie Driffort, Ludovic Gillet, Emeline Bon, Séverine Marionneau-Lambot, Thibauld Oullier, Virginie Joulin, Christine Collin, Jean-Christophe Pagès, Marie-Lise Jourdan, Stéphan Chevalier, Philippe Bougnoux, Pierre Besson, Sébastien Roger,
Molecular Cancer 2014
A coupling method for stochastic continuum models at diff erent scales,
Yves Le Guennec, Régis Cottereau, Didier Clouteau, Christian Soize,
Probabilistic Engineering Mechanics 2014
Isoprostanes and neuroprostanes: Total synthesis, biological activity and biomarkers of oxidative stress in humans,
Jean-Yves Le Guennec, Jean-Marie Galano, Emilie Mas, Anne Barden, Trevor Mori, Cinzia Signorini, Claudio De Felice, Aaron Barrett, Catherine Opere, Edith Pinot, Edzard Schwedhelm, Ralf Benndorf, Jérôme Roy, Camille Oger, Thierry Durand,
Prostaglandins & other lipid mediators 2013
The Orai-1 and STIM-1 Complex Controls Human Dendritic Cell Maturation,
Romain Félix, David Crottès, Anthony Delalande, Jérémy Fauconnier, Yvon Lebranchu, Jean-Yves Le Guennec, Florence Velge-Roussel,
PLoS ONE 2013
Long-chain acylcarnitines regulate the hERG channel,
Fabio Ferro, Aude Ouillé, Truong-An Tran, Pierre Fontanaud, Patrick Bois, Dominique Babuty, François Labarthe, Jean-Yves Le Guennec,
PLoS ONE 2012
Beneficial effects of omega-3 long-chain fatty acids in breast cancer and cardiovascular diseases: voltage-gated sodium channels as a common feature?,
Jean-Yves Le Guennec, Ludovic Gillet, Sébastien Roger, Philippe Bougnoux, Pierre Besson,
Biochimie 2011
The SK3/KCa2.3 potassium channel is a new cellular target for edelfosine,
Jean-Yves Le Guennec, P. Potier, C Chantome, V. Joulin, A Girault, S Roger, P Besson, M-L Jourdan, J-Y Leguennec, P. Bougnoux, C. Vandier,
British Journal of Pharmacology 2011
NaV1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H+ efflux in caveolae,
Jean-Yves Le Guennec, L Brisson, L Gillet, S Calaghan, P Besson, S Roger, J. Goré,
Oncogene 2011
A step towards characterisation of electrophysiological profile of torsadogenic drugs,
Jean-Yves Le Guennec, Pascal Champeroux, Aude Ouillé, Eric Martel, John Sinclair Lawrence Fowler, Anne Maurin, Serge Richard,
Journal of Pharmacological and Toxicological Methods 2011
New drugs vs. old concepts: A fresh look at antiarrhythmics,
Jean-Yves Le Guennec, Jérôme Thireau, Jean-Luc Pasquie, Eric Martel, Sylvain Richard,
Pharmacology & Therapeutics 2011
Interferences of the autonomic nervous system with drug induced QT prolongation: A point to consider in non-clinical safety studies,
Jean-Yves Le Guennec, Pascal Champeroux, Aude Ouillé, Eric Martel, John Sinclair Lawrence Fowler, Anne Maurin, Sébastien Judé, Patricia Lala, Serge Richard,
Journal of Pharmacological and Toxicological Methods 2010
Cardioprotection by omega-3 fatty acids: Involvement of PKCs?,
Jean-Yves Le Guennec, S. Jude, P. Besson, E. Martel, P. Champeroux,
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 2010
Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness,
Jean-Yves Le Guennec, Truong-An Tran, Ludovic Gillet, Sébastien Roger, Pierre Besson, Edward White,
Biochemical and Biophysical Research Communications 2009
Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells,
Jean-Yves Le Guennec, Ludovic Gillet, Sébastien Roger, Pierre Besson, Fabien Lecaille, Jacques Gore, Philippe Bougnoux, Gilles Lalmanach,
Journal of Biological Chemistry 2009
On the Mechanisms of Ultrasound Contrast Agents-Induced Arrhythmias,
Jean-Yves Le Guennec, Truong An Tran, Jean Yves Le Guennec, Dominique Babuty, Philippe Bougnoux, François Tranquart, Ayache Bouakaz,
Ultrasound in Medicine and Biology 2009
Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch,
Younss Ait Mou, Jean-Yves Le Guennec, Emilio Mosca, Pieter De Tombe, Olivier Cazorla,
Pflügers Archiv European Journal of Physiology 2008
Characterization of cell membrane response to ultrasound activated microbubbles,
Jean-Yves Le Guennec, Truong-An Tran, J.Y. Le Guennec, P. Bougnoux, F. Tranquart, A. Bouakaz,
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 2008
Voltage-gated ion channels, new targets in anti-cancer research,
Jean-Yves Le Guennec, Halima Ouadid-Ahidouch, Olivier Soriani, Pierre Besson, Ahmed Ahidouch, Christophe Vandier,
Recent Patents Anticancer Drug Discov 2007
Effect of ultrasound-activated microbubbles on the cell electrophysiological properties,
T. A. Tran, Sébastien Roger, Jean-Yves Le Guennec, François Tranquart, Ayache Bouakaz,
Ultrasound in Medicine and Biology 2007
Voltage-gated sodium channels potentiate the invasive capacities of human non-small-cell lung cancer cell lines,
Sébastien Roger, Jérôme Rollin, Aurélia Barascu, Pierre Besson, Pierre-Ivan Raynal, Sophie Iochmann, Ming Lei, Philippe Bougnoux, Yves Gruel, Jean-Yves Le Guennec,
International Journal of Biochemistry and Cell Biology 2007
Voltage-gated sodium channels: new targets in cancer therapy?,
Sébastien Roger, Marie Potier, Christophe Vandier, Pierre Besson, Jean-Yves Le Guennec,
Current Pharmaceutical Design 2006
Ca2+ currents in cardiac myocytes: Old story, new insights,
Fabien Brette, Jérôme Leroy, Jean-Yves Le Guennec, Laurent Sallé,
Progress in Biophysics and Molecular Biology 2006
Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers,
Sébastien Judé, Sébastien Roger, Eric Martel, Pierre Besson, Serge Richard, Philippe Bougnoux, Pascal Champeroux, Jean-Yves Le Guennec,
Progress in Biophysics and Molecular Biology 2006
Transmural stretch-dependent regulation of contractile properties in rat heart and its alteration after myocardial infarction,
Olivier Cazorla, Szabolcs Szilagyi, Jean-Yves Le Guennec, Guy Vassort, Alain Lacampagne,
FASEB Journal 2005
Length–Tension Relationships of Sub-epicardial and Sub-endocardial Single Ventricular Myocytes from Rat and Ferret Hearts,
Olivier Cazorla, Jean-Yves Le Guennec, Ed White,
Journal of Molecular and Cellular Cardiology 2000
EFFECTS ON L-TYPE CALCIUM CURRENT OF AGENTS INTERFERING WITH THE CYTOSKELETON OF ISOLATED GUINEA-PIG VENTRICULAR MYOCYTES,
Fabien Brette, Jean-Yves Le Guennec, Olivier Cazorla, Caroline Pascarel,
Experimental Physiology 1999
Length Modulation of Active Force in Rat Cardiac Myocytes: is Titin the Sensor?,
Olivier Cazorla, Guy Vassort, Didier Garnier, Jean-Yves Le Guennec,
Journal of Molecular and Cellular Cardiology 1999
Resting Tension Participates in the Modulation of Active Tension in Isolated Guinea Pig Ventricular Myocytes,
Olivier Cazorla, Caroline Pascarel, Didier Garnier, Jean-Yves Le Guennec,
Journal of Molecular and Cellular Cardiology 1997

Editorship

Implication des canaux sodiques inhibés par la TTX dans l'invasivité des cellules cancéreuses,
Sébastien Roger, Pierre Besson, Philippe Bougnoux, Jean-Yves Le Guennec,
2006